MSG is Harmful for Human Brain Health

Health Issues Regarding MSG

1. Chinese restaurant syndrome or Chinese Restaurant Syndrome (CRS)
Is a syndrome that appears after consuming Chinese cuisine is one of the reasons alleged MSG. The term CRS raised by Dr. Ho Man Kwok in 1968 in his essay to The New England Journal of Medicine.

The letter attracted the attention of the media and the general public so there is a negative perception about MSG until now. The researchers were motivated to prove the link between CRS and MSG. The latest study in 2000 which reported Geha et al.

The result: MSG in food does not cause a reaction CRS. Research Geha et al

In Indonesia, the study conducted by MSG and CRS Widharto et al, researchers from UGM (University of Gajah Mada-Yogyakarta) and Kelly, researchers from Australia to Indonesia 52 people healthier.

The result: Indonesia MSG in food does not cause CRS. Details Widharto research and Kelly.

2. Brain Damage
MSG and brain damage issues arising from research Olney in 1969.

Weaknesses research Olney:
a. Giving MSG force or by eating mice injections to infants, while the MSG provided with food through the digestive system
b. Doses of MSG given 0.5-4.0 g / kg body weight equivalent to 30-240 grams for a person weighing 60 kg, was not in accordance with the daily use of MSG, to taste the flavor of food

Research by Y. Takasaki et al (1978), Y Takasaki et al (1979), W. Pardrige (1979), J.Fernstrom (1994), Q.Smith (2000)
The conclusion of this study is:
Y. Takasaki et al (1978) = When MSG is given orally with food, plasma glutamate level does not change.
Y. Takasaki et al (1979) = MSG in the diet does not cause any acute or long-range adverse effect on the brain.
W. Pardrige (1979) = Dietary glutamate does not enter the blood brain barrier.
J.Fernstrom (1994) = Dietary glutamate does not prsesnt any risk to normal brain function.
Q.Smith (2000) = Brain glutamate is kept constan Independently from the circulatory system.

3. Pregnant Women and Fetus
Research by Stegink et al (1979) in monkeys in the third month of pregnancy.
The results: MSG is injected fluid does not affect the fetus because the placenta.

A recent study by Battaglia (2000) showed that the fetus itself produces glutamate (MSG largest component). Glutamate is produced by the fetal liver which is then used by the placenta as a source of energy.

4. Cancer
Cancer is a group of diseases characterized by the body's cell growth is uncontrolled. The general opinion of medical experts about the cause of the cancer risk from eating habits foods that contain high levels of fat and salt, but less consumption of fibrous foods.

There are several studies that reported incidence of cancer causing ingredients are cooking or burning of high protein foods such as meat at very high temperatures above 200 ° C. The food is processed at temperatures tend to be charcoal and unfit for consumption.

While the way that everyday cooking stir frying, boiling, steaming, and frying have less heating temperature of 200 ° C.

MSG is cooked with food by cooking a reasonable not cause cancer.

5. Baldness
Undergo hair growth and hair loss that death is a process of daily life reasonable. However, losing more than 100 strands of hair per day may be an early indication of baldness.

A common cause of baldness is genetic, due to the influence of hormones that cause thinning of the hair resulting in baldness.

Glutamate (MSG largest component) is a protein constituent amino acids hair. MSG is added to food does not cause baldness.

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MSG is a food additive that most researched over a period of 40 years. Research carried out both on the security and benefits of MSG & Glutamate (MSG as the largest component). Accurate information about glutamate can be obtained at the International Glutamate Information Service (IGIS), which bases its information on the scientific evidence

Some recent research about MSG and glutamate, among others:

Glutamate metabolism in the body
The study was conducted by Peter J. Reeds, Douglas G Burrin, Barbara Stoll, and Farook Jahoor of the Dept. of Pediatrics, Baylor College of Medicine, Houston, Texas, USA. Presented at the International Symposium of Glutamate to-2 in 1998, in Bergamo, Italy, and has been published in The Journal of Nutrition in 2000.

Research results:
1. Glutamate is the largest source of energy in the small intestine. Studies using piglets, 95% glutamate from food is metabolized by the small intestine where 50% are metabolized to CO2
2. Glutamate from the food serves as a specific precursor for glutathione biosynthesis, arginine and proline in the small intestine.

Subsequent research conducted by Douglas G. Burrin, Michael J. Janeczko, and Barbara Stoll of the Dept. of Pediatrics, Baylor College of Medicine Houston, Texas, USA. Presented at the Asian Nutrition Congress in 2007, in Taiwan and has been published in the Asian Pacific Journal of Clinical Nutrition in 2008 paper entitled "Emerging aspect of dietary glutamate metabolism in the developing gut".

Research results indicate psychological glutamate transport in the stomach has a significant role and the need for further research regarding the role of MSG in the formation and function of the stomach in infants.

Effect of glutamate on people special diet
The study was conducted in France in 1998 by France Bellisle of the Unite de Rechercheen epidemologie Nutritionnelle, Bobigny, France. Presented at the Asian Nutrition Congress in 2007, in Taiwan and has been published in the Asian Pacific Journal of Clinical Nutrition in 2008 paper entitled "Experimental studies of food choices and palatability responses in European subjects exposed to the Umami taste".

Research results:

Research subjects parents / elderly amounted to 65 people with an average age of 84 years who have low appetite problems resulting in risk of malnutrition. Methods of research subjects were given a menu with food target (source of calcium / magnesium and Ca / Mg) with and without MSG.
Research results, increased food consumption targets without changing the total meal size (total calories constant) and the total intake of calcium and magnesium subject to increase.
Research subject numbered 62 people with diabetes who need balanced nutrition though subjects had abnormal hormone insulin. Methods of research subjects were given a menu with foods that have targeted low glycemic index with and without MSG. The results of the study, food consumption target is increased without changing the total meal size and total energy intake did not change due to the consumption of other foods that are served after meals reduced targets.

Effect of glutamate on digestion
Research in Japan in 2007 by Hisayuki Uneyama, Ana San Gabriel, Misako Kawai, and Kunio Miki Tomoe Torii of Ajinomoto Institute of Life Science and Division of Nutritional RS Okanoki. Presented at the Asian Nutrition Congress in 2007, in Taiwan and has been published in the Asian Pacific Journal of Clinical Nutrition in 2008 paper entitled "Physiological role of dietary free glutamate in the food digestion".

Research results:
a. Glutamate receptors in the tongue in addition there was also in the stomach.
b. Glutamate from the food in the stomach (and mouth) causes glutamate receptors send signals to the brain (via afferent nerves) to instruct the stomach and pancreas (via efferent nerves) to produce digestive juices. Useful digestive juices to break down food in the stomach and small intestine into the nutrients needed by the body. So indirectly glutamate (MSG largest component) helps the body's digestive process.

Source in here.